Contraindicated Substances for G6PD Deficient Patients

See g6pddeficiency.org for more information.

Avoid moth balls, artificial blue food color, legumes (fava beans, beans, peas, peanuts, soy, lentils, etc.), sulfites, tonic water. Please read all labels on processed foods before feeding to patient.

Substances labeled Low Risk MAY be given safely at normal therapeutic doses UNLESS the patient is severely G6PD Deficient or has chronic non-spherocytic hemolytic anemia. There is no guarantee that low risk drugs will not cause hemolysis. Please see g6pddeficiency.org for more information.

A diet rich in antioxidant foods is recommended to help minimize the effects of oxidative stress and the resultant hemolysis. Vitamins b6, b12, folic acid and NAC are also important.

Acetaminophen - Low RiskNiridazole - High Risk
Acetanilid - High RiskNitrofurantoin - High Risk
Acetylphenylhydrazine - High RiskNitrofurazone - High Risk
Aminophenazone - High RiskNorfloxacin - Low Risk
Antazoline - Low RiskOxidase, Urate - High Risk
Antipyrine - Low RiskPamaquine - High Risk
Ascorbic Acid - Low RiskPara-Aminobenzoic Acid - Low Risk
Aspirin - High RiskPefloxacin - High Risk
Astemizole - RiskPentaquine - High Risk
Beta-Naphthol - High RiskPhenacetin - High Risk
Celebrex - High RiskPhenazopyridine - High Risk
Chloramphenicol - High RiskPhenylbutazone - Low Risk
Chloroquine - High RiskPhenylhydrazine - High Risk
Ciprofloxacin - High RiskPhenytoin - Low Risk
Colchicine - Low RiskPrimaquine - High Risk
Dapsone - High RiskProbenecid - High Risk
Dimercaprol - High RiskProcainamide - Low Risk
Diphenhydramine - Low RiskProguanil - Low Risk
Dopamine - Low RiskPyrimethamine - Low Risk
Doxorubicin - High RiskQuinacrine - High Risk
Ethanol - High RiskQuinidine - Low Risk
Furazolidone - High RiskQuinine - Low Risk
Furosemide - High RiskStibophen - High Risk
Gadopentetate dimeglumine - High RiskStreptomycin - Low Risk
Glucosulfone - High RiskSulfacetamide - High Risk
Glyburide - High RiskSulfacytine - Low Risk
Henna - High RiskSulfadiazine - Low Risk
Ibuprofen - Low RiskSulfadimidine - High Risk
Isobutyl Nitrite - High RiskSulfafurazole - High Risk
Isoniazid - Low RiskSulfaguanidine - Low Risk
Lamotrigine - High RiskSulfamerazine - Low Risk
Levofloxacin - High RiskSulfamethoxazole - High Risk
Lisinopril - high RiskSulfamethoxypyridazine - Low Risk
Magnevist - RiskSulfanilamide - High Risk
Mefloquine - High RiskSulfapyridine - High Risk
Menadiol Sodium Sulfate (Vitamin k4 sodium sulfate) - High RiskSulfasalazine - High Risk
Menadione - High RiskSulfathiazole - High Risk
Menadione sodium Bisulfite (Vitamin K3 sodium bisulfite) - High RiskSulfonylurea - Low Risk
Menthol - High RiskSulfoxone - High Risk
Mesalazine - High RiskTamsulosin - High Risk
Metformin - High RiskTiaprofenic Acid - Low Risk
Methylene Blue - High RiskToluidine Blue - High Risk
Mirtazapine - Low RiskTrihexyphenidyl - Low Risk
Moxifloxacin - High RiskTrimethoprim - Low Risk
Nalidixic Acid - High RiskTrinitrotoluene - High Risk
Naphthalene - High RiskTripelennamine - Low Risk
Nimesulide - High RiskVitamin K1 - Low Risk