G6PD Deficiency Inheritance Chart

The G6PD Deficiency inheritance chart below shows how one or both of parents pass the X linked G6PDD gene to their children. It cannot be passed from one person to another in any other way. Males can either be G6PD Deficient or unaffected. Females can be G6PD Deficient, partially deficient (sometimes erroneously known as carriers) or unaffected.

The following rules determine the probability of inheritance with each pregnancy.

G6PD Deficiency Inheritance Chart

MotherFather UnaffectedFather Affected
UnaffectedAll children UnaffectedAll boys Unaffected
All girls Partially Deficient
Partially DeficientBoys 50% chance Affected
Girls 50% chance partially deficient
Boys 50% chance Affected
Girls 50% chance of being Partially Deficient or Fully Deficient
Fully DeficientBoys All Deficient
Girls All Partially Deficient
Boys All Deficient
Girls All Fully Deficient

 

Father is UNAFFECTED, mother is UNAFFECTED.

  • ALL of their children will be UNAFFECTED.

Father is G6PD DEFICIENT, mother is UNAFFECTED.

      • All sons will be UNAFFECTED.
      • All daughters will be PARTIALLY DEFICIENT.

Father is G6PD DEFICIENT, mother is PARTIALLY DEFICIENT.

      • Boys 50% chance G6PD DEFICIENT.
      • Girls 50% chance of being PARTIALLY DEFICIENT or G6PD DEFICIENT.

Father and mother are G6PD DEFICIENT.

  • All children will be G6PD DEFICIENT.

Father is UNAFFECTED, mother is PARTIALLY DEFICIENT.

  • Boys 50% chance G6PD DEFICIENT.
  • Girls 50% chance of being PARTIALLY DEFICIENT.

Father is UNAFFECTED, mother is G6PD DEFICIENT.

  • All sons will be G6PD DEFICIENT.
  • All daughters will be PARTIALLY DEFICIENT.
G6PD Deficiency Inheritance Chart was last modified: September 24th, 2016 by Dale Baker