G6PD Deficiency and chemotherapy can be a complex and hazardous combination. I received a letter from a woman who has a G6PDD boyfriend undergoing chemotherapy. They gave him rasburicase which caused severe hemolysis and almost killed him. After I answered her questions she sent the following email.
“Thank you so much for the answer. We are not alone with this deficiency anymore. The doctors are using your website as a guide for his treatment. Do you know of any chemoterapy drugs to avoid? The doctors are using the hypercvad protocol. We are avoiding doxorrubicin and rasburicase. Thank you again for the answers. Probably his case will became a paper, talking about the g6pd deficiency in the chemotherapy treatment.”
The goal for chemotherapy is to bring the patient as close to death as possible because the cancer cells die before the patient. Theoretically. Unfortunately, for those with G6PDD, chemotherapy can cause hemolysis. Stress by itself and any substance that causes oxidative stress can cause hemolysis.
G6PD Deficiency and Chemotherapy suggestions.
- During chemotherapy fill him full of antioxidants.All he can eat.
- Feed him liver and grape juice every day.
- Take as much NAC as the doctors will allow.
- Talk to the doctors about how much B vitamins he can safely take. Give his body as much help as possible to produce red blood cells.
- Vitamin E has been known to help with cancer and is a great antioxidant. Ask his doctors how much he can safely take.
- Avoid everything on the foods to avoid list on http://g6pddeficiency.org/wp/ like the plague.
- Ask the doctors if you can provide his food if he has to go to the hospital. Make his food from scratch from organic or farmer’s market foods.
Problems to discuss with his doctors:
- Spleen – it takes the brunt of the job of removing dead blood cells and can fail during long periods of hemolysis.
- Liver – medication that is metabolized through the liver should be avoided as much as possible. The liver is adversely affected by G6PDD. Liver cancer is common with G6PDD patients.
- Eyes – dead red blood cells can clog the small veins of the eyes and cause loss or impairment of eyesight.
- Bones – enlarged bones can result from over production of red blood cells.
- Heart – the heart has to work extra hard to provide nutrients and oxygen to the rest of the body. Help that process as much as possible.